Evidence map›Paper›PMID 42558672›Full record

ArticleFrontiers in immunology2026

Rapid-onset massive immune-mediated pericardial effusion in a patient with anti-IFN-γ autoantibodies syndrome.

Fushou Chen, Yan Ning, Hanlin Liang, Jiaqi Qin, Siqiao Liang, Xuemei Huang, Xiaona Liang, Feixiang Tan, Ni Chen, Siyao Wu and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fushou Chen *Department of Respiratory and Critical Care Medicine, Wuming Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yan Ning *Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Hanlin Liang *Department of Respiratory and Critical Care Medicine, Wuming Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jiaqi Qin *Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Siqiao LiangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Xuemei HuangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Xiaona LiangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Feixiang TanDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Ni ChenDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Siyao WuDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Limei HongDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Zhiyi HeDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Tao FengDepartment of Respiratory and Critical Care Medicine, Wuming Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anti-interferon-gamma (IFN-γ) autoantibodies (AIGAs) syndrome is an emerging adult-onset immunodeficiency (AOID) associated with opportunistic infections and immune dysregulation. Pericardial effusion as a direct manifestation of this syndrome is rarely reported. Case presentation: A 46-year-old man with a history of Conclusion: This case highlights pericardial effusion as a potential immune-mediated complication of AIGAs syndrome. Clinicians should consider this diagnosis in patients with unexplained serositis and a history of opportunistic infections.

Indexed as

AutoantibodiesAutoimmune DiseasesInterferon-gammaPericardial EffusionHumansMaleMiddle AgedMycobacterium Infections, NontuberculousOpportunistic InfectionsTalaromycesAutoantibodiesInterferon-gammaanti-IFN-γ autoantibodies syndromecase reportimmune dysregulationnontuberculous mycobacteriapericardial effusionTalaromyces marneffei

Identifiers

PMID42558672
PMCPMC13438186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.