ArticleFrontiers in medicine2026
The interaction between illness perception and intrinsic capacity during hospital-to-home transition in older adults with COPD and diabetes: a prospective cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the changes, bidirectional relationships, and moderating factors of illness perception and intrinsic capacity in older adults with COPD and Type 2 Diabetes Mellitus (T2DM) during the hospital-to-home transition. Methods: A prospective cohort study was conducted from April 2024 to September 2025, conveniently enrolling 232 older adults with COPD and T2DM from the Sixth People's Hospital of Nantong. Participants were assessed at three time points: at discharge (T0), 1 month (T1), and 3 months (T2) post-discharge, using the Brief Illness Perception Questionnaire (BIPQ) and a WHO framework-based intrinsic capacity assessment tool. A Random-intercept cross-lagged panel model (RI-CLPM) was used to analyze the dynamic cross-lagged relationships, a Latent growth model (LGM) was used to analyze the association of their change trajectories, and exploratory subgroup analyses were performed. Results: (1) Trajectory analysis: Illness perception total scores showed a consistent and significant decreasing trend across the three time points ( Conclusion: During the hospital-to-home transition, illness perception and intrinsic capacity in older adults with COPD and T2DM exhibit a dynamic interaction, characterized by bidirectional influences in the early stage and a more sustained effect of intrinsic capacity on perception later. COPD severity and baseline vitality status are important clinical moderators of this relationship. The findings provide a basis for developing targeted transition care strategies that integrate psychological and functional interventions for high-risk subgroups.
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