Evidence map›Paper›PMID 42558475›Full record

ArticleFrontiers in surgery2026

Efficacy evaluation of urethral dragging-and-adhesion anastomosis in ileal orthotopic neobladder reconstruction following laparoscopic radical cystectomy: a dual-center retrospective study.

Lie Yu Xu, Xin Chang Zou, Qing Wen Luo, Hai Chao Chao, Zun Wei Zhu, Xiang Da Xu, Tao Zeng

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Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lie Yu Xu *Department of Urology, Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College), Nanchang, China.
Xin Chang Zou *The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Qing Wen LuoThe Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Hai Chao ChaoDepartment of Urology, Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zun Wei ZhuDepartment of Urology, Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College), Nanchang, China.
Xiang Da XuDepartment of Urology, Second Affiliated Hospital of Nanchang University, Nanchang, China.
Tao ZengDepartment of Urology, Second Affiliated Hospital of Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Urethra-neobladder anastomosis following laparoscopic radical cystectomy combined with an ileal orthotopic neobladder is a pivotal step that significantly influences postoperative urinary continence, urodynamic performance, and the risk of surgical complications. Purpose: This study aims to evaluate the effects of a modified urethral dragging-and-adhesion anastomosis technique on postoperative urodynamic parameters, urinary continence recovery, and immune function, with emphasis on its potential benefits in reducing surgical trauma, enhancing functional outcomes, and mitigating immune suppression. Patients and methods: A retrospective analysis was performed on 55 patients with bladder cancer who underwent laparoscopic radical cystectomy with ileal orthotopic neobladder reconstruction at Jiangxi Provincial People's Hospital (35 cases) and the Second Affiliated Hospital of Nanchang University (20 cases) between June 2016 and January 2021. Of these, 30 patients received urethral dragging-and-adhesion anastomosis (observation group), while 25 patients underwent conventional interrupted anastomosis (control group). The study compared operative time and intraoperative blood loss between the two groups and evaluated postoperative urodynamic parameters, including maximum bladder capacity, postvoid residual, maximum flow rate (Q-max), and average flow rate (Q-ave). In addition, this study evaluated the recovery of daytime and nighttime urinary control in patients 3 months, 1 year, and 2 years after the surgery, along with immune function indicators 1 week after the surgery, namely, the proportions of CD3+, CD4+, and CD8+ T cells and the CD4+/CD8+ ratio. Results: There were no significant differences in preoperative general data or immune-related parameters between the two groups. The observation group demonstrated significantly shorter operative times (279.80 ± 45.32 min vs. 382.60 ± 45.94 min, Conclusion: Urethral dragging-and-adhesion anastomosis is a safe and effective modified technique for urethral reconstruction during laparoscopic radical cystectomy with an ileal orthotopic neobladder. It enables speedy surgical completion and urethral anastomosis while preserving urodynamic and urinary continence functions comparable to those of traditional methods. In addition, it may contribute to better preservation of patients' immune function.

Indexed as

dragging-and-adhesion anastomosisimmune functionlaparoscopic radical cystectomyorthotopic neobladderurodynamics

Identifiers

PMID42558475
PMCPMC13437787

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