Evidence map›Paper›PMID 42558453›Full record

ArticleFrontiers in medicine2026

Efficacy and safety of airway clearance techniques in Chinese adult patients with pneumonia: a systematic review and meta-analysis.

Hongyun Cai, Lijing Wang, Wei Yuan, Ying Qi

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongyun Cai *Department of Cardiovascular, Affiliated Hospital of Hebei University, Lianchi District, Baoding City, Hebei Province, China.
Lijing Wang *Department of Neurology, Affiliated Hospital of Hebei University, Lianchi District, Baoding City, Hebei Province, China.
Wei YuanDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Hebei University, Lianchi District, Baoding City, Hebei Province, China.
Ying QiDepartment of Tuberculosis, Affiliated Hospital of Hebei University, Lianchi District, Baoding City, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This systematic review and meta-analysis aimed to synthesize the available evidence from Chinese randomized controlled trials to evaluate the efficacy and safety of airway clearance techniques compared to conventional treatment in adult patients with pneumonia, including stroke-associated pneumonia, severe viral pneumonia, and severe pneumonia requiring mechanical ventilation. Methods: We systematically searched PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang databases from inception to January 1, 2026, for randomized controlled trials (RCTs) comparing airway clearance techniques plus conventional treatment Results: Eleven randomized controlled trials were included. Meta-analysis showed airway clearance techniques significantly increased treatment effectiveness (OR 3.83, 95% CI 2.04-7.16; I Conclusion: In conclusion, this meta-analysis provides hypothesis-generating evidence that airway clearance techniques may improve treatment effectiveness, reduce complications, and enhance oxygenation in Chinese adult patients with pneumonia. However, due to heterogeneity, methodological limitations, and lack of long-term patient-centered outcomes, these findings require confirmation in future international multicenter trials.

Indexed as

critical carephysical therapy modalitiespneumoniarespiratory therapysystematic review

Identifiers

PMID42558453
PMCPMC13437794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.