ArticleFrontiers in oncology2026
Palliative gastrectomy or gastrojejunostomy for symptomatic stage IV gastric cancer: a dual center, retrospective, propensity matched cohort study.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Palliative surgery is considered to release symptoms for symptomatic stage IV gastric cancer (GC) patients. However, whether palliative gastrectomy or gastrojejunostomy should be conducted was still controversial. Therefore, the current study aims to compare the long-term prognosis of palliative gastrectomy and gastrojejunostomy for symptomatic stage IV GC patients. Methods: Symptomatic stage IV GC patients in the China-Japan Friendship Hospital and China National Cancer Center between January 2000 to December 2023 were retrospectively reviewed. The short-term safety and long-term survival outcomes were compared between palliative gastrectomy and gastrojejunostomy for symptomatic stage IV GC patients. A 1:1 propensity score matching (PSM) was performed to balance covariates between groups. Results: In total, 2705 gastric cancer with stage IV were retrieved and finally 197 individuals were therefore enrolled in the study based on the search and inclusion and exclusion criteria. Compared with palliative gastrectomy group, palliative gastrojejunostomy group had shorter operation time ( Conclusions: Palliative gastrectomy might provide no survival benefit compared with Gastrojejunostomy for symptomatic stage IV gastric cancer. However, further multicenter, prospective studies with a larger sample size were needed to verify these findings.
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