Evidence map›Paper›PMID 42558320›Full record

ArticleFrontiers in immunology2026

Fermentable fiber supplementation in pigs promotes anti-parasitic defense mechanisms and impacts parasite growth in

Philipp Höfler, Josephine Schlosser-Brandenburg, Arkadi Kundik, Sebastian Rausch, Eva-Maria Saliu, Larissa Oser, Anja A Kühl, Robert M Mugo, Alexandra Laubschat, Zaneta Musimbi Kidiavai and 4 more

Abstract read
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In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Philipp HöflerDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Josephine Schlosser-BrandenburgMethodology and Research Infrastructure, Animal Experimental Research and 3R (MF3), Robert-Koch-Institute, Berlin, Germany.
Arkadi KundikDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Sebastian RauschDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Eva-Maria SaliuDepartment for Landscape, Society and Economy, University of Applied Science for Sustainable Development, Eberswalde, Germany.
Larissa OserDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Anja A KühlCharité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, iPATH.Berlin, Core unit of Charité, Campus Benjamin Franklin, Berlin, Germany.
Robert M MugoDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Alexandra LaubschatDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Zaneta Musimbi KidiavaiDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Ankur MidhaDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Robert KlopfleischDepartment of Veterinary, Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
Jürgen ZentekDepartment of Veterinary Medicine, Institute of Animal Nutrition, Freie Universität Berlin, Berlin, Germany.
Susanne HartmannDepartment of Veterinary Medicine, Institute of Immunology, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ascarids are among the most prevalent soil-transmitted helminths affecting both humans and livestock, particularly pigs. While reduced anthelmintic efficacy has been reported in humans, frequent reinfection and the lack of a vaccine highlight the need for alternative control strategies across species. In pigs, fermentable dietary fibers have been shown to enhance type 2 immune responses and mucosal barrier function and may represent a complementary strategy for parasite control. Here, we investigated the effects of a fermentable fiber diet in pigs infected with the parasite

Indexed as

AscariasisAscaris suumDietary FiberDietary SupplementsSwine DiseasesAnimalsFemaleFermentationSwineTh2 CellsDietary FiberAscaris suumdietary fiberhelminth infectionpigporcine models

Identifiers

PMID42558320
PMCPMC13437497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.