Evidence map›Paper›PMID 42557923›Full record

ArticleMagnetic resonance in medicine2026

Correlating Pulmonary Hemodynamics With HP

Markus Phillip Andersen, Mattias Hedegaard Kristensen, Esben Søvsø Szocska Hansen, Rolf F Schulte, Mohsen Redda, Uffe Kjærgaard, Michael Vaeggemose, Christoffer Laustsen

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Markus Phillip AndersenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0009-0008-6112-0280
Mattias Hedegaard KristensenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Esben Søvsø Szocska HansenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0000-0001-5512-9870
Rolf F SchulteGE HealthCare, Munich, Germany.
Mohsen ReddaMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Uffe KjærgaardMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0000-0002-9188-2162
Michael VaeggemoseMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0000-0001-7666-6819
Christoffer LaustsenMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0000-0002-0317-2911

Funding

A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal 23/1-2021Karen Elise Jensens Fond 30/6-2022
6 · The paper itself

Abstract

purposePulmonary hypertension is related to a 1-year mortality ranging from < 5% to > 20% in low- and high-risk groups. Right heart catheterization is the diagnostic gold standard, associated with a 1.1% rate of severe adverse events, posing the need for a non-invasive diagnostic tool. This study aims to delineate the effects of controlled changes on pulmonary hemodynamics by quantifying corresponding changes in hyperpolarized

methodsSeven Danish Landrace pigs underwent hyperpolarized

resultsHypoxia increased mPAP (p = 0.038), reduced RBC:M (-31%, p = 0.007) and RBC:G (-34%, p = 0.009), while increasing RBC chemical shift (0.57%, p = 0.020). Adenosine and dobutamine increased RBC:M (22%, p = 0.003) and RBC:G (30%, p = 0.009), while decreasing RBC chemical shift (-0.38%, p = 0.11). Linear regression revealed an inverse correlation between mPAP and RBC oscillation amplitude (R

conclusionThis study demonstrates that dissolved-phase hyperpolarized

Indexed as

HemodynamicsHypertension, PulmonaryLungMagnetic Resonance ImagingXenon IsotopesAnimalsCardiac CatheterizationDobutamineFemaleMagnetic Resonance SpectroscopyPulmonary CirculationSwineDobutamineXenon Isotopescardiopulmonary hemodynamicsdissolved‐phase MRSIhyperpolarized xenonlungpulmonary hypertensionright heart catheterization

Identifiers

PMID42557923
PMCPMC13619864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.