Evidence map›Paper›PMID 42557744›Full record

ArticleAdvanced healthcare materials2026

Gradient Zinc-Doping Strategy Combined With Tumor Metabolic Interference for Effective Catalytic Immunotherapy.

Chang Liu, Jing Wang, Weili Xue, Wenkang Tu, Xuwu Zhang, Zhiwei Liu, Xiaoling Li, Xiyun Yan, Yuchu He, Dawei Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chang LiuState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Jing WangState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Weili XueState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Wenkang TuState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Xuwu ZhangState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.ORCID https://orcid.org/0000-0002-2461-8599
Zhiwei LiuState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Xiaoling LiState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.
Xiyun YanCAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing, P. R. China.ORCID https://orcid.org/0000-0002-7290-352X
Yuchu HeState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.ORCID https://orcid.org/0009-0009-4723-2312
Dawei GaoState Key Laboratory of Metastable Materials Science and Technology, Nano-biotechnology Key Lab of Hebei Province, Applying Chemistry Key Lab of Hebei Province, Shenzhen Research Institute, Yanshan University, Qinhuangdao, P. R. China.ORCID https://orcid.org/0000-0002-5030-7022

Funding

Cultivation Project for Basic Research and Innovation of Yanshan University 2023LGQN008Cultivation Project for Basic Research and Innovation of Yanshan University 2024LGQN014National Natural Science Foundation 22078280National Natural Science Foundation 22108235National Natural Science Foundation 22208282National Natural Science Foundation 22278349National Natural Science Foundation 22478333National Natural Science Foundation of China U21A20309Science and Technology Plan Project of Qinhuangdao City 202303B002Science Research Project of Hebei Education Department BJK2024046S&T Program of Hebei 236Z2703GS&T Program of Hebei 246Z2704G
6 · The paper itself

Abstract

Photocatalytic immunotherapy has attracted significant attention due to high selectivity and low side effects. However, the poor tissue penetration of ultraviolet-visible light and the low energy of near-infrared (NIR) photons, combined with the immunosuppressive tumor microenvironment (TME), severely limit catalytic efficiency and immune activation. In this study, we designed a gradient Zn

Indexed as

ImmunotherapyZincAnimalsCatalysisCell Line, TumorHumansMiceMice, Inbred BALB CNitrilesTumor MicroenvironmentcyanogenNitrilesZincenergy metabolismimmunosuppressiveion gradientnear‐infrared lightphotocatalytic immunotherapy

Identifiers

PMID42557744
PMCPMC13542944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.