Evidence map›Paper›PMID 42557510›Full record

ReviewScience China. Life sciences2026

Organelle-specific fluorescent probes for live imaging at the nanoscale.

Tianyan Liu, Zhenzhen Zhang, Zhixing Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tianyan Liu *College of Future Technology, Institute of Molecular Medicine, National Biomedical Imaging Center, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, 100871, China.
Zhenzhen Zhang *Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, South China Normal University, Guangzhou, 510631, China.
Zhixing ChenCollege of Future Technology, Institute of Molecular Medicine, National Biomedical Imaging Center, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, 100871, China. zhixingchen@pku.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular organelles are structures within cells that compartmentalize biochemical reactions for advanced cellular functions. Historically, synthetic dyes that target various cellular targets have been the mainstay for modern cell biology, which are subsequently supplemented by genetically encodable fluorescent proteins. Recently, the optically privileged organic dyes have rejuvenated as indispensable tools for live-cell super-resolution (SR) imaging, including self-targeting probes for organelle labeling and self-labeling ligands that label genetically encoded protein tags (i.e., SNAP and Halo tags). In this review, we provide an overview of recent developments in design strategies and bioimaging applications of synthetic fluorescent probes for imaging organelles. We aim to provide a fluorescent dye-selection guide for cell biologists, while also offering an outlook on the potential directions of future research.

Indexed as

fluorescent probeslive-cell imagingorganelle labelingsuper-resolution

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.