ArticleMikrochimica acta2026
Light-controlled molecular recognition of aflatoxins using azobenzene photo-switchable molecularly imprinted materials.
Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Early detection of aflatoxins is crucial to safeguard food safety. In this study, a new azobenzene monomer was synthesized and its photo-isomerization behavior in methanol and dimethyl sulfoxide was studied. A photo-switchable molecularly imprinted polymer (PMIP) designed for selectively recognizing aflatoxin B1 (AFB1) was fabricated via a surface imprinting technique. A dummy template, 5,7-dimethoxycoumarin was incorporated during the polymerization process. The photo-responsive behaviors of candidate monomers were systematically evaluated in methanol and dimethyl sulfoxide. The resulting PMIP was used as an extraction adsorbent for pretreatment prior to high-performance liquid chromatography-mass spectrometry analysis with its adsorption capacity could be controlled by light irradiation (365 nm and 440 nm). The method demonstrated a linear calibration interval from 50 to 1000 ng·mL⁻¹ with detection limit of 5.1 ng·mL⁻¹, and exhibited favorable binding capacity values between 90.8% and 95.4% when used for the determination of AFB1 in corn, reflecting the strong recognition affinity of PMIP toward AFB1.
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