Evidence map›Paper›PMID 42557333›Full record

ArticleNature2026

An ancient mitochondrial program tunes translation to haem availability.

Xiang Zhang, Max-Hinderk Schuler, Gonca Çetin, Eva-Maria Eckl, Lara Rheinemann, Julia Mergner, Barbara Steigenberger, Andreas Pichlmair, Lucas T Jae

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiang Zhang *Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID http://orcid.org/0000-0002-1007-7007
Max-Hinderk Schuler *Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID http://orcid.org/0000-0002-6734-8250
Gonca ÇetinGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Eva-Maria EcklGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Lara RheinemannInstitute of Virology, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-4314-0172
Julia MergnerBavarian Center for Biomolecular Mass Spectrometry at University Hospital Rechts der Isar (BayBioMS@MRI), School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-4332-1280
Barbara SteigenbergerMass Spectrometry Core Facility, Max Planck Institute of Biochemistry, Martinsried, Germany.
Andreas PichlmairInstitute of Virology, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-0166-1367
Lucas T JaeGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany. l.jae@lmu.de.ORCID http://orcid.org/0000-0002-3531-1760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaemia is a major global health burden that affects one-quarter of the human population and annually accounts for over 50 million years of healthy life lost

Indexed as

HemeMitochondriaProtein BiosynthesisAnimalsCytosoleIF-2 KinaseFetal HemoglobinHumansMitochondrial ProteinseIF-2 KinaseFetal HemoglobinHemeMitochondrial Proteins

Identifiers

PMID42557333
PMCPMC13600944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.