Evidence map›Paper›PMID 42557314›Full record

ArticleNature2026

Stimulation modulates gene-linked cell assemblies in the human brain.

Haley Moore, Mantre Dehnad, Anne Freelin, Bryan Granger, Suganya Subramanian, Tjitse van der Molen, Ashwinikumar Kulkarni, Stefano Berto, Bradley C Lega, Genevieve Konopka

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Haley MooreDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-4562-6774
Mantre DehnadDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Anne FreelinO'Donnell Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-9998-7914
Bryan GrangerDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.ORCID http://orcid.org/0009-0008-6663-3755
Suganya SubramanianDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.ORCID http://orcid.org/0009-0007-2822-9420
Tjitse van der MolenDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Ashwinikumar KulkarniDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Stefano BertoDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.ORCID http://orcid.org/0000-0001-9028-9458
Bradley C LegaDepartment of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA. bradley.lega@utsouthwestern.edu.ORCID http://orcid.org/0000-0003-3634-406X
Genevieve KonopkaDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA. gkonopka@mednet.ucla.edu.ORCID http://orcid.org/0000-0002-3363-7302

Funding

Deciphering the genomic mechanisms underlying the physiology of human brain stimulationR01NS126143 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Genevieve Konopka, Bradley C Lega · 2025 to 2026
$2.2M
NINDS NIH HHS R01 NS126143
6 · The paper itself

Abstract

Reshaping cortical circuits through stimulation represents an emerging therapy for the restoration of cognitive function

Indexed as

BrainGene Regulatory NetworksTemporal LobeFemaleHumansMaleMicroelectrodesNeurons

Identifiers

PMID42557314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.