ArticleNature2026
Virus reactivation in acute and long COVID-19.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Role of Angiotensin-Converting Enzyme 2 in Response to SARS-CoV-2 in the Host With Metabolic Dysfunction.JACC. Basic to translational science · 2026Article
- When do infections lead to long COVID? Scientists close in on triggers and treatments for post-viral syndromes.Nature · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
59 authors.
Cole MaguireDell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0001-8986-9762
Jing ChenClinical and Data Coordinating Center (CDCC) Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0009-0006-5900-7460
Nadine RouphaelEmory School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-2512-7919
Brinkley A MorseDell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0009-0008-1304-2716
Annmarie HochClinical and Data Coordinating Center (CDCC) Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0836-2164
Harry PickeringDavid Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
Hoang Van PhanUniversity of California San Francisco, San Francisco, CA, USA.
Abigail GlascockChan Zuckerberg Biohub, San Francisco, CA, USA.
Victoria ChuUniversity of California San Francisco, San Francisco, CA, USA.
Ravi DandekarUniversity of California San Francisco, San Francisco, CA, USA.
IMPACC Network
David CorryBaylor College of Medicine and the Center for Translational Research on Inflammatory Diseases, Houston, TX, USA.ORCID http://orcid.org/0000-0001-9729-1016
Farrah KheradmandBaylor College of Medicine and the Center for Translational Research on Inflammatory Diseases, Houston, TX, USA.ORCID http://orcid.org/0000-0001-5343-103X
Lindsey R BadenBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0009-0004-1752-1926
Rafick-Pierre SekalyCase Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-7816-4828
Grace A McComseyCase Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA.ORCID http://orcid.org/0000-0003-2690-8888
Elias K HaddadDrexel University, Drexel University College of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-6924-4300
Charles B CairnsDrexel University, Drexel University College of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-2291-5415
Bali PulendranStanford University School of Medicine, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0001-6517-4333
Ana Fernandez-SesmaIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-3405-6702
Viviana SimonIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-6416-5096
Jordan P MetcalfOklahoma University Health Sciences Center, Oklahoma City, OK, USA.ORCID http://orcid.org/0000-0003-4359-5270
Nelson I Agudelo HiguitaOklahoma University Health Sciences Center, Oklahoma City, OK, USA.ORCID http://orcid.org/0000-0002-9363-6280
William B MesserOregon Health Sciences University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-4381-6347
Mark M DavisStanford University School of Medicine, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0001-6868-657X
Kari C NadeauStanford University School of Medicine, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-2146-2955
Monica KraftUniversity of Arizona, Tucson, AZ, USA.
Chris BimeUniversity of Arizona, Tucson, AZ, USA.
Joanna SchaenmanDavid Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
David ErleUniversity of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2171-0648
Carolyn S CalfeeUniversity of California San Francisco, San Francisco, CA, USA.
Mark A AtkinsonUniversity of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0001-8489-4782
Scott C BrakenridgeUniversity of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-7327-3718
Lauren I R EhrlichThe University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0002-1697-1755
Ruth R MontgomeryYale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-8661-4454
Albert ShawYale School of Medicine, New Haven, CT, USA.
Catherine L HoughOregon Health Sciences University, Portland, OR, USA.
David HaflerYale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-4664-535X
Alison D AugustineNational Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.
Patrice M BeckerNational Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-1170-8587
Bjoern PetersLa Jolla Institute for Immunology, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-8457-6693
Al OzonoffClinical and Data Coordinating Center (CDCC) Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4233-5899
Seunghee Kim-SchulzeIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-0192-4400
Florian KrammerIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4121-776X
Steven E BosingerEmory School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-2116-5061
Walter EckalbarUniversity of California San Francisco, San Francisco, CA, USA.
Matthew C AltmanBenaroya Research Institute, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-1784-8505
Michael WilsonUniversity of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-8705-5084
Leying GuanYale School of Public Health, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-0609-1073
Steven H KleinsteinYale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-4957-1544
Kinga K SmolenPrecision Vaccines Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8650-3693
Elaine F ReedDavid Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
Ofer LevyPrecision Vaccines Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5859-1945
Holden MaeckerStanford University School of Medicine, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0003-0795-9946
Peter HuntUniversity of California San Francisco, San Francisco, CA, USA.
Hanno SteenPrecision Vaccines Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0179-6648
Joann Diray-ArceClinical and Data Coordinating Center (CDCC) Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2183-4269
Charles R LangelierUniversity of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-6708-4646
Esther MelamedDell Medical School, The University of Texas at Austin, Austin, TX, USA. esther.melamed@austin.utexas.edu.ORCID http://orcid.org/0000-0001-5571-3591
Funding
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0MClinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1MNCATS NIH HHS UM1 TR004528NIH HHS P51 OD011132
Abstract
Chronic viral infections are ubiquitous in humans, with individuals carrying multiple viruses that can reactivate during physiological stress, including severe illness
Indexed as
Post-Acute COVID-19 SyndromeSARS-CoV-2Virus ActivationAcute DiseaseCOVID-19FemaleHumansLongitudinal StudiesMultiomicsPersistent InfectionSeverity of Illness IndexTime Factors
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.