Evidence map›Paper›PMID 42556984›Full record

ReviewClinics in perinatology2026

Antibiotic Therapy for the Prevention and Treatment of Neonatal Sepsis.

Sarah A Coggins, Karen M Puopolo

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah A CogginsDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: cogginss@chop.edu.
Karen M PuopoloDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Transplacental Antibiotic Exposures in Newborn InfantsK23HD119271 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Sarah A Coggins · 2025 to 2026
$320k
NICHD NIH HHS K23 HD119271
6 · The paper itself

Abstract

Antibiotics are among the most commonly prescribed medications in neonatal intensive care units. Preterm and term infants are commonly exposed to antibiotics: before birth via transplacental intrapartum maternal exposures, at birth due to suspected early-onset sepsis, or due to suspected late-onset sepsis in the first weeks to months of a neonatal intensive care unit hospitalization. Antibiotic selection requires assessment of infection timing and associated microbiology patterns, patient-specific factors (eg, colonization status, source of infection), and antibiotic resistance concerns. In this article, we summarize basic concepts relevant to neonatal antimicrobial pharmacology and available neonatal-specific pharmacokinetic/pharmacodynamic data for commonly-used antibiotic agents.

Indexed as

Anti-Bacterial AgentsNeonatal SepsisFemaleHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalAnti-Bacterial AgentsAntibioticInfantInfectionNeonatePharmacology

Identifiers

PMID42556984
PMCPMC13447996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.