ArticleChemistry & biodiversity2026
Chemical Constituents with UT-B Inhibitory Activity from Astragalus rigidulus.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The whole plant of Astragalus rigidulus Benth. ex Bunge (Fabaceae) has been employed in Tibet to clear lung heat, alleviate diarrhea and edema. In the present study, a phytochemical investigation of A. rigidulus led to the isolation of a new alkaloid, n-butyl hematinate (1), and a new benzyl ester, astrigioside A (2), along with twenty known analogs (3-22). Their structures were elucidated through comprehensive spectroscopic analysis, including 1D/2D NMR, UV, IR, HR-ESI-MS, and comparison of the spectroscopic data with those reported in literatures. The UT-B inhibitory activities of all isolates were evaluated by erythrocyte lysis assay model. As a result, compounds 7, 8, 10, and 18 possessed significant UT-B inhibitory effects, with IC
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