Evidence map›Paper›PMID 42555678›Full record

ArticleeLife2026

High-throughput quantification of population dynamics using luminescence.

Malte Muetter, Daniel C Angst, Roland Regoes, Sebastian Bonhoeffer

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Malte MuetterDepartment of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0009-0005-9262-7306
Daniel C AngstDepartment of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0002-6512-4595
Roland RegoesDepartment of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-8319-5293
Sebastian BonhoefferDepartment of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-8052-3925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial population decline at antibiotic concentrations above the minimum inhibitory concentration (MIC) remains poorly characterized. This is because colony-forming units (CFU), the standard method to quantify inhibition, are slow, labor-intensive, and costly. Luminescence assays are widely used to quantify population dynamics at subinhibitory concentrations, yet their limitations and reliability at high concentrations remain underexplored. Here, we compared luminescence- and CFU-based rates in

Indexed as

Anti-Bacterial AgentsEscherichia coliHigh-Throughput Screening AssaysLuminescenceLuminescent MeasurementsColony Count, MicrobialMicrobial Sensitivity TestsAnti-Bacterial Agentsantibioticsbioluminescencecolony-forming unitsE. coliinfectious diseasemicrobiologypharmacodynamicstime-kill curves

Identifiers

PMID42555678
PMCPMC13441296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.