Evidence map›Paper›PMID 42555566›Full record

ArticlePLoS computational biology2026

GeneInsight: Condensing gene set knowledge via language models.

Wee Loong Chin, Kevin Chen, Timo Lassmann

Abstract read
In one paragraph

Article in PLoS computational biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wee Loong ChinNational Centre for Asbestos-Related Diseases, University of Western Australia, Perth, Western Australia, Australia.ORCID 0000-0002-2549-3601
Kevin ChenThe Kids Research Institute Australia, University of Western Australia, Nedlands, Western Australia, Australia.
Timo LassmannThe Kids Research Institute Australia, University of Western Australia, Nedlands, Western Australia, Australia.ORCID 0000-0002-0138-2691

Funding

Cancer Research Trust, Western AustraliaFeilman FoundationStan Perron Charitable Foundation
6 · The paper itself

Abstract

Gene set analysis often returns extensive annotations from multiple sources, requiring manual effort to identify coherent biological themes. We developed GeneInsight, an AI-powered tool that automates this by retrieving functional annotations from STRING-DB, clustering semantically related terms using sentence embeddings, and generating thematic summaries via large language model prompting. This enables researchers to identify biological themes that may be obscured when annotation sources are examined separately.

Indexed as

Computational BiologyMolecular Sequence AnnotationSoftwareDatabases, GeneticHumansLarge Language ModelsNatural Language Processing

Identifiers

PMID42555566
PMCPMC13440848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.