Evidence map›Paper›PMID 42555525›Full record

ReviewPhysiotherapy research international : the journal for researchers and clinicians in physical therapy2026

Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction.

Ehab A Abdallah, Ahmed M Elshinnawy, Mahmoud Diab Abdelhaleem

Abstract readReview
In one paragraph

Review in Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ehab A AbdallahDepartment of Orthopedic Physical Therapy, Faculty of Physical Therapy, Horus University, New Damietta, Egypt.ORCID https://orcid.org/0009-0003-3359-1046
Ahmed M ElshinnawyDepartment of Physical Therapy for Neuromuscular Disorders and its Surgery, Faculty of Physical Therapy, Merit University, Sohag, Egypt.ORCID https://orcid.org/0000-0001-5678-0841
Mahmoud Diab AbdelhaleemDepartment of Orthopedic Physical Therapy, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic ankle instability and chronic low back pain are highly prevalent in musculoskeletal conditions. Emerging evidence suggests that they are interconnected through shared biomechanical, neuromuscular, and neurophysiological mechanisms, where deficits in proprioception, postural control, and load distribution contribute to persistent dysfunction across the kinetic chain.

methodsThis study employed a narrative review with a conceptual framework, incorporating evidence from biomechanical, neuromuscular, and neurophysiological studies found through targeted database searches (PubMed, Scopus, and Google Scholar 2019-2025). Findings were thematically analyzed to establish connections between distal and proximal dysfunction within the kinetic chain.

resultsA total of 23 studies were included. Overall, the evidence suggests consistent distal-to-proximal alterations in individuals with chronic ankle instability, including impaired ankle biomechanics, compensatory lumbopelvic movement patterns, and deficits in proprioception and neuromuscular control. Emerging findings also indicate neurophysiological adaptations affecting sensorimotor integration. Collectively, these findings suggest a potential association between chronic ankle instability and chronic low back pain.

conclusionChronic ankle instability and chronic low back pain may coexist within a functionally interconnected kinetic system. Recognizing their potential interdependence supports a model of multi-segmental stability and highlights the importance of combined ankle-core rehabilitation strategies.

Indexed as

Ankle JointChronic PainJoint InstabilityLow Back PainBiomechanical PhenomenaChronic DiseaseHumansPostural BalanceProprioceptionbiomechanical interdependencechronic ankle instabilitykinetic chainlow back painlumbopelvic controlsensorimotor integration

Identifiers

PMID42555525
PMCPMC13440686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.