Evidence map›Paper›PMID 42555402›Full record

ArticleRSC advances2026

Identification of quinoline scaffolds against emerging drug target glycerophosphodiester phosphodiesterase from

Zainab, Uzma Salar, Faiza Seraj, Syeda Sumayya Tariq, Reaz Uddin, Syed Abid Ali, Khalid Mohammed Khan

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

ZainabH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan abid.ali@iccs.edu khalid.khan@iccs.edu.
Uzma SalarDr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan uzma_salar_sheikh@hotmail.com uzma.salar@iccs.edu +9221111222292.ORCID https://orcid.org/0000-0003-1871-9112
Faiza SerajH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan abid.ali@iccs.edu khalid.khan@iccs.edu.
Syeda Sumayya TariqDr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan uzma_salar_sheikh@hotmail.com uzma.salar@iccs.edu +9221111222292.
Reaz UddinDr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan uzma_salar_sheikh@hotmail.com uzma.salar@iccs.edu +9221111222292.
Syed Abid AliH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan abid.ali@iccs.edu khalid.khan@iccs.edu.
Khalid Mohammed KhanH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan abid.ali@iccs.edu khalid.khan@iccs.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycerophosphodiester phosphodiesterases (GDPDs) are biocatalysts and highly conserved enzymes in both prokaryotic and eukaryotic organisms. GDPD plays an important role in cellular metabolism by hydrolyzing glycerophosphodiester substrates into smaller but useful molecules, such as glycerol-3-phosphate and its corresponding alcohol. GDPD directly affects the pathogenicity of infectious bacteria, including

Identifiers

PMID42555402
PMCPMC13330723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.