Evidence map›Paper›PMID 42554733›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2026

Characterizing Comorbidities in Total Joint Arthroplasty in a Safety-Net Hospital Using Age-Adjusted Charlson Comorbidity Index.

Matthew Chan, Lily Khabie, Noshin Nuzhat, Melanie Anaya, Gabriela de Queiroz Campos, Ira Kirschenbaum

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Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Matthew ChanFrom the Department of Orthopedics (Chan, Dr. Kirschenbaum), BronxCare Health System, Bronx, NY; the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell (Khabie), Uniondale, NY; the University of Arizona College of Medicine (Nuzhat), Tucson, AZ; the The Warren Alpert Medical School of Brown University (Anaya), Providence, RI; and the The Mount Sinai Hospital (Dr. de Queiroz Campos), New York City, NY.ORCID 0009-0001-7384-2191
Lily Khabie
Noshin Nuzhat
Melanie Anaya
Gabriela de Queiroz Campos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe joint arthroplasty population has a high number of comorbidities at the time of surgery, which increases the cost of care per episode. The goal of this study was to analyze the distribution of comorbid diseases in patients who have undergone total joint arthroplasty at our institution, which serves the poorest congressional district in the United States. We hypothesized that patients in an urban safety-net hospital would have higher comorbidity rates and higher Charlson Comorbidity Indices and that this would suggest the need for improved risk stratification in payment systems.

methodsA retrospective analysis was conducted by reviewing consecutive patients who underwent total joint arthroplasty between 2008 and 2023 (N = 3011). Relevant comorbidities were used to calculate the age-adjusted Charlson Comorbidity Index. From this, we determined the score distribution and identified the most frequent conditions. Descriptive statistical analysis was conducted to determine the mean and variance.

resultsWithin the patient population concerning CCI scores, 10.93% of the patient population scored 0, 22.42% scored 1, 27.33% scored 2, 20.86% scored 3, 10.73% scored 4, and 7.74% scored 5 and above. The mean CCI score was 2.25 ± 1.50. The most frequently occurring comorbid conditions according to hospital criteria in this population were hypertension (N = 2078, 69.01%), obesity (N = 1366, 45.37%), diabetes (N = 906, 30.09%), and anemia (N = 694, 23.05%). A total of 19.10% of patients were current smokers. Of all TJA patients, 96.9% had at least 1 comorbidity.

conclusionThe major finding from this retrospective analysis revealed the presence of a high incidence of comorbidities in the our health system's total joint arthroplasty population. We confirmed that this closed urban population is a unique subset of at-risk individuals who are undergoing TJA, which may increase their complication rates. Consideration for proper risk stratification in communities like this need to be considered.

Indexed as

Arthroplasty, ReplacementArthroplasty, Replacement, HipComorbiditySafety-net ProvidersAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk Factors

Identifiers

PMID42554733
PMCPMC13395510

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.