Evidence map›Paper›PMID 42554629›Full record

ArticleAntimicrobial agents and chemotherapy2026

Emergence of

Shaoji Cheng, Cornelius J Clancy, Giuseppe Fleres, Hassan Badrane, Matthew J Culyba, Anthony Newbrough, Liang Chen, M Hong Nguyen

Abstract read
PubMed Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Shaoji ChengDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0009-0000-5055-0543
Cornelius J ClancyDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1750-4005
Giuseppe FleresDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hassan BadraneDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0009-0009-7412-0199
Matthew J CulybaDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-8327-4135
Anthony NewbroughDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Liang ChenDepartment of Pharmacy and Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, New York, USA.ORCID 0000-0001-5845-2235
M Hong NguyenDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2065-3239

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
NIAID NIH HHS UM1 AI104681NIH HHS R21A1166847NIH HHS UM1AI104681
6 · The paper itself

Abstract

Hypermutation-driven evolution is a major contributor to antibiotic resistance in some bacterial pathogens, but its role in

Indexed as

Anti-Bacterial AgentsCarbapenemsDNA Mismatch RepairKlebsiella pneumoniaeAnimalsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCefiderocolCeftazidimeDrug CombinationsDrug Resistance, Multiple, BacterialHumansKlebsiella InfectionsMiceMicrobial Sensitivity TestsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCarbapenemsCefiderocolCeftazidimeDrug CombinationsThird Generation Cephalosporinscarbapenem-resistantDNA mismatch proteinhypermutatorKlebsiella pneumoniaeMutH

Identifiers

PMID42554629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.