Evidence map›Paper›PMID 42554478›Full record

ArticlemBio2026

Jana Gomez, Jesus Duran-Ramirez, Maristhela Alvarez, Shane Cristy, Jennifer N Walker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Carbapenem-resistantbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jana GomezDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Jesus Duran-RamirezDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.ORCID 0000-0003-0907-0550
Maristhela AlvarezDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Shane CristyDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Jennifer N WalkerDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.ORCID 0000-0002-0079-3261

Funding

Defining Host-pathogen Interactions in CAUTI to Guide Novel Drug DevelopmentK01DK128381 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Jennifer Nicole Walker · 2022 to 2026
$691k
American Heart Association 25PRE1372661NIDDK NIH HHS K01 DK128381NIDDK NIH HHS K01 DK128381-01A1
6 · The paper itself

Abstract

Catheter-associated urinary tract infections (CAUTIs) are one of the most common hospital-associated infections in the United States, accounting for >1 million cases annually. One CAUTI pathogen, IMPORTANCE: In this study, we investigate how regulatory pathways coordinate the expression and activity of urease in response to environmental signals present within the catheterized urinary tract. We show that growth during the post-exponential phase and in conditions that mimic the urinary tract increases urease expression and activity. This finding challenges the dogma that

Indexed as

Catheter-Related InfectionsGene Expression Regulation, BacterialGene Regulatory NetworksStaphylococcal InfectionsStaphylococcus aureusUreaseUrinary Tract InfectionsAnimalsBacterial ProteinsHumansMiceVirulence FactorsBacterial ProteinsUreaseVirulence Factorscatheter-associated urinary tract infectionsgene regulationStaphylococcus aureusurease

Identifiers

PMID42554478
PMCPMC13556217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.