Evidence map›Paper›PMID 42554470›Full record

ArticleMicrobiology spectrum2026

Short linear motifs-underexplored players driving

Jesús Alvarado Valverde, Karine Lapouge, Arne Boergel, Kim Remans, Katja Luck, Toby J Gibson

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesús Alvarado ValverdeStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-0752-1151
Karine LapougeProtein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-0620-9553
Arne BoergelProtein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0002-0323-6989
Kim RemansProtein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0002-4394-7953
Katja LuckInstitute of Molecular Biology (IMB) gGmbH, Mainz, Germany.ORCID 0000-0003-2336-9225
Toby J GibsonStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-0657-5166

Funding

Deutsche Forschungsgemeinschaft 449991970
6 · The paper itself

Abstract

Pathogens infect hosts by interacting with host proteins and exploiting their functions to their advantage. Short linear motifs, small functional regions within intrinsically disordered protein regions, are common mediators of host-pathogen protein interactions. While motifs have been more extensively studied in viruses and bacteria, the extent to which eukaryotic unicellular parasites use motifs during infection remains poorly explored.

Indexed as

Protozoan ProteinsToxoplasmaToxoplasmosisAmino Acid MotifsAnimalsComputational BiologyHost-Parasite InteractionsHost-Pathogen InteractionsHumansProtein BindingProtozoan Proteinshost-pathogen interactionsprotein-protein interactionsshort linear motifsToxoplasma gondii

Identifiers

PMID42554470
PMCPMC13532356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.