Evidence map›Paper›PMID 42554398›Full record

ArticleJACC. Asia2026

Validated Polygenic Risk Scores Complement Monogenic Testing in South Asian Patients With Familial Hypercholesterolemia.

Nithya Abraham, Ramesh Menon, Praveen V Pavithran, Lavina Udhwani, Akshi Bassi, Praveena L Samson, Rammurthy Anjanappa, Ravi Gupta, Ramprasad Vedam L, Usha Menon and 4 more

Abstract read
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In one paragraph

Article in JACC. Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nithya AbrahamDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India. Electronic address: nithya21039@aims.amrita.edu.
Ramesh MenonMedGenome Labs Ltd, Bangalore, India.
Praveen V PavithranDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India.
Lavina UdhwaniMedGenome Labs Ltd, Bangalore, India.
Akshi BassiMedGenome Labs Ltd, Bangalore, India.
Praveena L SamsonMedGenome Labs Ltd, Bangalore, India.
Rammurthy AnjanappaMedGenome Labs Ltd, Bangalore, India.
Ravi GuptaMedGenome Labs Ltd, Bangalore, India.
Ramprasad Vedam LMedGenome Labs Ltd, Bangalore, India.
Usha MenonDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India.
Nisha BhavaniDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India.
Vasantha NairDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India.
Harish KumarDepartment of Endocrinology, Amrita Vishwa Vidyapeetham, Amrita School of Medicine, AIMS Ponekkara, Kochi, Kerala, India.
Devaki R NairUniversity College of London and Royal Free London NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

genome-wide association studyLDL-PRSPRS modelssingle nucleotide polymorphismvariant

Identifiers

PMID42554398
PMCPMC13458952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.