ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2026
Validation of an Automated Artificial Intelligence-Driven Planner for Transcatheter Aortic Valve Replacement.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPreprocedural planning with multislice computed tomography (MSCT) is an essential prerequisite for successful transcatheter aortic valve replacement (TAVR). However, preprocedural planning is time-consuming and may contain clinically meaningful interobserver variability. Artificial intelligence (AI) based automated planning methods may provide anatomical MSCT measurements while reducing the time load required for the analysis. Previous studies on the validation of AI-based TAVR planning methods excluded anatomical variants or lacked data on actual TAVR prosthesis size agreement. Mimics for TAVR (Materialise, Leuven, Belgium) is a new, AI-driven TAVR planning platform based on patient-specific 3D anatomical models and automated measurements through a web-based user interface.
aimsTo validate the Mimics for TAVR planning tool in clinical practice.
methodsKey planning assessments were performed on pre-TAVR MSCT datasets using Mimics for TAVR and a commercially available semi-automated software package. Agreement between the two planning methods was assessed using intraclass correlation coefficients and Bland-Altman plots.
resultsA total of 126 consecutive patients (mean age 80 [74-85]; 56% male) who underwent MSCT as part of their TAVR work-up were included. Mimics for TAVR derived measurements showcased high accuracy and excellent agreement for the area of the aortic annulus (mean error ± SD: -1.9 ± 3.3%, ICC: 0.976 [95% CI: 0.966-0.984]), left ventricular outflow (-2.7 ± 3.8%, ICC: 0.970 [0.957-0.983]), sinotubular junction (-2.6 ± 4.2%, ICC: 0.953 [0.921-0.971]), coronary heights (LCA -3.5 ± 4.8%, ICC: 0.900 (0.859-0.928). RCA -3.9 ± 4.7%, ICC: 0.928 [0.898-0.949]) and membranous septum length (-5.0 ± 9.2%, ICC: 0.919 [0.880-0.940]). Mimics for TAVR assessment significantly reduced the time required for pre-TAVR analysis (1.03 ± 0.15 min vs. 9.55 ± 3.16 min per case, respectively (p = 0.001).
conclusionThe automated AI-driven Mimics for TAVR planner is an accurate alternative to existing semiautomated TAVR planning platforms and may enhance overall workflow efficiency.
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