Evidence map›Paper›PMID 42553956›Full record

ArticleGE Portuguese journal of gastroenterology

Verrucous Carcinoma of the Esophagus: A Deceiving Entity with an Uncertain Etiology - Case Report.

Isabel Malta Carvalho, Tânia Gago, Luís Relvas, Margarida Portugal, Jesus Cadilla, Bruno Peixe

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in GE Portuguese journal of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabel Malta CarvalhoGastroenterology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.
Tânia GagoGastroenterology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.
Luís RelvasGastroenterology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.
Margarida PortugalGastroenterology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.
Jesus CadillaPathology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.
Bruno PeixeGastroenterology Department, Unidade Local de Saúde do Algarve, Faro, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Verrucous carcinoma of the esophagus is an extremely rare malignancy, described as a well-differentiated variant of esophageal squamous cell carcinoma, typically exhibiting exophytic/verrucous growth and intraluminal involvement that is often rich in inflammation and hyperkeratosis, which hampers histologic diagnosis and consequently delays treatment. We report the case of a 58-year-old woman with progressive dysphagia and a circumferential, verrucous esophageal lesion, without histologic confirmation despite multiple biopsies and endoscopic resections, showing only focal p16 positivity. After further evaluation with CT, endoscopic ultrasound, and FDG-PET/CT, a presumptive diagnosis of locally advanced verrucous carcinoma of the esophagus was assumed, and palliative chemotherapy was initiated, followed by a sustained endoscopic and radiologic response. This case highlights the importance of multidisciplinary discussion when verrucous carcinoma of the esophagus is suspected and the unexpected, sustained response despite unresectability.

Indexed as

Case reportEsophageal neoplasmMalignant stenosisVerrucous carcinoma

Identifiers

PMID42553956
PMCPMC13436934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.