Evidence map›Paper›PMID 42553806›Full record

ArticleEuropean heart journal. Case reports2026

A case report of an S-ICD-recorded asystole due to SMART pass deactivation in a patient with non-obstructive hypertrophic cardiomyopathy.

Marie Lajos, Wim Rother, Thomas Hucko, Kristof Graf, Sebastian Spencker

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In one paragraph

Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Marie LajosDepartment of Internal Medicine-Invasive Cardiology, Electrophysiology and Intensive Care Medicine, Jüdisches Krankenhaus Berlin, Heinz-Galinski Straße 1, Berlin 13347, Germany.ORCID https://orcid.org/0009-0002-5593-142X
Wim RotherDepartment of Internal Medicine-Invasive Cardiology, Electrophysiology and Intensive Care Medicine, Jüdisches Krankenhaus Berlin, Heinz-Galinski Straße 1, Berlin 13347, Germany.
Thomas HuckoDepartment of Internal Medicine-Invasive Cardiology, Electrophysiology and Intensive Care Medicine, Jüdisches Krankenhaus Berlin, Heinz-Galinski Straße 1, Berlin 13347, Germany.
Kristof GrafDepartment of Internal Medicine-Invasive Cardiology, Electrophysiology and Intensive Care Medicine, Jüdisches Krankenhaus Berlin, Heinz-Galinski Straße 1, Berlin 13347, Germany.
Sebastian SpenckerDepartment of Internal Medicine-Invasive Cardiology, Electrophysiology and Intensive Care Medicine, Jüdisches Krankenhaus Berlin, Heinz-Galinski Straße 1, Berlin 13347, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The SMART pass (SP) algorithm of the subcutaneous implantable cardioverter-defibrillator (S-ICD; Boston Scientific Emblem) uses a high-pass filter to reduce inappropriate shocks due to signal oversensing. In cases of small to no R-wave amplitude, the SP algorithm is automatically deactivated, and an electrocardiogram (ECG) is recorded. Case Summary: A 63-year-old patient with hypertrophic cardiomyopathy (HCM) without left ventricular outflow tract obstruction underwent implantation of an S-ICD. When the patient reported syncope months later, device interrogation revealed SP deactivation due to a 22-second asystole, consistent with the timing of the syncope. Prior to the event, there was no indication of future pacing requirement. The patient had a stable two-vessel coronary artery disease as well as unaltered echocardiographic findings, including preserved left ventricular ejection fraction. The S-ICD was replaced by a transvenous dual-chamber implantable cardioverter-defibrillator. Discussion: Although bradycardia detection is not available in the S-ICD system, in our case, it was enabled due to ECG recording performed during SP deactivation, which outlines the importance of careful investigation. Since bradyarrhythmia in HCM is considered rare, it has been studied far less extensively than atrial and ventricular tachyarrhythmia. There is substantial evidence that myocardial fibrosis is a significant predictor of ventricular tachycardia and sudden cardiac death. However, more extended research is required to further investigate the association between myocardial fibrosis and bradyarrhythmia in patients with HCM, as well as to evaluate the potential of magnetic resonance imaging-based screening to identify patients at risk requiring future pacing.

Indexed as

AsystoleCase reportHypertrophic cardiomyopathyS-ICDSMART pass deactivation

Identifiers

PMID42553806
PMCPMC13436686

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