Evidence map›Paper›PMID 42553714›Full record

ArticleOrganic process research & development2026

Hydroxyapatite as an Enzyme Carrier in Continuous-Flow Biocatalysis: An Improved Synthesis of γ‑Glutamyl Derivatives.

Leonardo Gelati, Fabrizio Medici, Sebastiano Campisi, Cinzia Calvio, Maurizio Benaglia, Antonella Gervasini, Marco Rabuffetti, Giovanna Speranza, Carlo F Morelli

Abstract read
In one paragraph

Article in Organic process research & development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leonardo GelatiDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.
Fabrizio MediciDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0003-1356-7244
Sebastiano CampisiDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0002-5496-7482
Cinzia CalvioDipartimento di Biologia e Biotecnologie, Università degli Studi di Pavia, via Ferrata 9, 27100 Pavia, Italy.ORCID https://orcid.org/0000-0003-1631-0452
Maurizio BenagliaDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0002-9568-9642
Antonella GervasiniDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0001-6525-7948
Marco RabuffettiDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.
Giovanna SperanzaDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0003-4544-1515
Carlo F MorelliDipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0001-6314-6902

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biocatalysis has proved to be of great importance to pursue a more sustainable production of fine chemicals, and enzyme immobilization is a crucial tool to achieve this goal. In this work, hydroxyapatite, an eco-friendly material, was used as a support for the immobilization of a γ-glutamyltransferase from

Indexed as

continuous-flow reaction γ-l-glutamyl-S-allyl-l-cysteineenzyme immobilizationenzyme reusabilityhydroxyapatiteγ-glutamyltransferase

Identifiers

PMID42553714
PMCPMC13436615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.