Evidence map›Paper›PMID 42553706›Full record

ArticleFrontiers in public health2026

Health Mode On and Health Mode On Plus: a multisite protocol to assess and promote mental wellbeing and healthy lifestyles among Italian university students.

Giacomo Pietro Vigezzi, Giansanto Mosconi, Giovanni Albini, Silvio Brusaferro, Anna Carli, Michele Emdin, Fabrizio Faggiano, Anna Ogliari, Alfredo Raglio, Caterina Rizzo and 3 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giacomo Pietro Vigezzi *Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Giansanto Mosconi *Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Giovanni AlbiniConservatory of Music Antonio Vivaldi, Alessandria, Italy.
Silvio BrusaferroDepartment of Medicine, University of Udine, Udine, Italy.
Anna CarliConservatory of Music Rinaldo Franci, Siena, Italy.
Michele EmdinInterdisciplinary Research Center for Health Science, Sant'Anna School of Advanced Studies, Pisa, Italy.
Fabrizio FaggianoDepartment of Sustainable Development and Ecological Transition, University of Eastern Piedmont, Vercelli, Italy.
Anna OgliariFaculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy.
Alfredo RaglioConservatory of Music Giuseppe Verdi, Milan, Italy.
Caterina RizzoDepartment of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy.
Emanuele RossiConservatory of Music Pietro Mascagni, Livorno, Italy.
Anna OdoneDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Health Mode On Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: University is a pivotal life-course transition in which academic, social and geographic changes intersect with heightened risk for mental disorders and maladaptive behaviors. Health Mode On (HMO) and its longitudinal expansion Health Mode On Plus (HMO+), funded by the Italian Ministry of University and Research (MUR) competitive PRO-BEN 1 and PRO-BEN 2 calls, couple harmonized surveillance with a stepped, integrated model of prevention and care aligned with the World Mental Health-International College Student (WMH-ICS) framework to address fragmentation of campus provision and unmet need. Methods and analysis: HMO implements a cross-sectional, census-style online survey paired with the implementation of an integrated counseling pathway and a Virtual Academy for staff and student mentors. HMO+ adds 12-month re-contact, objective lifestyle sub-studies, and a strengthened shared digital platform that supports first-contact intake, triage, and orientation to the most appropriate service. Within this framework, students with an anxiety risk profile may be offered participation in an embedded two-arm randomized evaluation of digital cognitive-behavioral therapy (e-CBT) versus counseling-as-usual. The consortium spans five universities, four higher artistic and musical education (AFAM) institutes and one Scuola Superiore Universitaria, in coordination with University Sports Centres (CUS). Primary outcomes are 12-month and lifetime DSM-5 disorder status derived from validated WMH-ICS/CIDI-based modules (mood; anxiety; trauma- and stressor-related; obsessive-compulsive and related; eating; attention-deficit/hyperactivity; and substance use disorders), and safety outcomes (suicidal ideation, planning and non-suicidal self-injury). Secondary outcomes include psychological distress, role impairment, days-out-of-role, sleep, physical activity (accelerometry in subsamples), dietary habits, nicotine and cannabis use, behavioral addictions (e.g., gaming, gambling, internet addiction), social connectedness, academic engagement and service access. Analyses will estimate weighted prevalence and impairment with multilevel models; longitudinal change with mixed-effects models and GEE; and naturalistic program effects using difference-in-differences with propensity-score methods. Ethics and dissemination: Ethics approvals will be obtained at the coordinating and partner institutions. GDPR-compliant governance and results' FAIR-oriented sharing are planned, alongside open-access publications, institutional dashboards and policy briefs.

Indexed as

Health PromotionHealthy LifestyleMental HealthStudentsCross-Sectional StudiesFemaleHumansItalyMalePsychological Well-BeingUniversitiesYoung Adultaddictive behaviorsdigital mental healthlongitudinal studiesmental healthuniversity students

Identifiers

PMID42553706
PMCPMC13435841

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.