ArticleOpen forum infectious diseases2026
Hepatitis C Treatment Outcomes Among Immigrants: A CANUHC Cohort Analysis.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
9 authors.
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Abstract
Background: Immigrants to Canada are disproportionately affected by hepatitis C virus (HCV) infection. Little is known about treatment outcomes among immigrants at the national level or how outcomes vary across Canadian provinces. Methods: We used data from the Canadian Network Undertaking against Hepatitis C (CANUHC), a prospective cohort enrolling HCV RNA-positive patients from 17 sites across 6 Canadian provinces between 2015 and 2025. Sociodemographic data, clinical characteristics, immigration details, time to first consult, and treatment outcomes were evaluated. Treatment outcomes included direct-acting antiviral (DAA) initiation, sustained virological response (SVR) bloodwork completion, and SVR achievement. Results: Of 2521 patients, 427 (16.9%) were immigrants to Canada. Immigrants had higher educational attainment (60.8% vs 28.2% college/university, Conclusions: Immigrants in the CANUHC cohort achieved excellent DAA treatment outcomes comparable to or exceeding those of Canadian-born patients. When engaged in care, immigrants can successfully complete the HCV treatment cascade.
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