Evidence map›Paper›PMID 42553678›Full record

ReviewAsian biomedicine : research, reviews and news2026

Gut-testis axis: how microbiota influence male reproductive health.

Ruiyang Hu, Jingxing Wu, Nianben Chen, Wenjun Ma, Qinglin Hu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Asian biomedicine : research, reviews and news, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruiyang HuDepartment of Clinical Medicine, The Second Clinical Medical College of Anhui Medical University, Hefei 230032, Anhui, China.
Jingxing WuThe First Clinical Medical College of Anhui University of Chinese Medicine, Hefei 230022, Anhui, China.
Nianben ChenThe First Clinical Medical College of Anhui University of Chinese Medicine, Hefei 230022, Anhui, China.
Wenjun MaDepartment of Urology, Chuzhou Integrated Hospital of Chinese and Western Medicine, Affiliated to Anhui University of Traditional Chinese Medicine, Chuzhou, China.
Qinglin HuDepartment of Urology, Chuzhou Integrated Hospital of Chinese and Western Medicine, Affiliated to Anhui University of Traditional Chinese Medicine, Chuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal flora forms a complex ecosystem that interacts with the host, influencing health and fitness through mechanisms that connect with distant organs like the brain, liver, muscles, and testes. The gut microbiota plays a vital role in regulating androgen production and metabolism, and can cross the blood-testis barrier to influence spermatogenesis. This review highlights the significance of the gut-testis axis in male reproductive and sexual health, based on extensive studies exploring how gut microbes impact testicular function. Gaining this understanding deepens our knowledge of the gut-testis axis and its role in male reproductive health.

Indexed as

gastrointestinal microbiomegut dysbiosisgut–testis axismale reproductive healthmen’s healthmicrobiotatestis

Identifiers

PMID42553678
PMCPMC13435932

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.