ArticleFrontiers in neuroscience2026
Reduced binaural masking release in women with migraine despite normal hearing: a case-control study.
Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Migraine is a neurological disorder associated with altered sensory processing, including auditory hypersensitivity. Although peripheral hearing is typically normal, central auditory mechanisms-particularly binaural interaction-may be affected. The masking level difference (MLD) test evaluates binaural processing at the level of the auditory brainstem. Methods: This case-control study included 30 female patients with migraine and 35 age-matched healthy controls. All participants had normal otoscopic findings, type A tympanograms, and normal pure-tone thresholds. MLD testing was performed at 500 Hz. and 60 dB under homophasic (S Results: Pure-tone thresholds were within normal limits but significantly higher in the migraine group ( Conclusion: Migraine patients demonstrate reduced binaural masking release despite normal peripheral hearing, suggesting impaired brainstem-level binaural processing. These findings support altered central auditory function in migraine and may reflect broader subcortical sensory dysfunction.
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