Evidence map›Paper›PMID 42553616›Full record

ArticleCase reports in veterinary medicine2026

Synchronous Multiple Primary Tumors in a Dog: A Case Report.

Mohammad Reza Foroughi-Gilvaee, Nadi Maazi, Negin Raazi, Ahad Muhammadnejad

Abstract read
In one paragraph

Article in Case reports in veterinary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synchronous Multiple Primary Tumors in a Dog: A Case Report.Case reports in veterinary medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad Reza Foroughi-GilvaeeDepartment of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0001-6318-6496
Nadi MaaziDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran, ut.ac.ir.ORCID https://orcid.org/0009-0000-0607-6944
Negin RaaziDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran, azad.ac.ir.ORCID https://orcid.org/0009-0002-4325-4695
Ahad MuhammadnejadCancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-5936-4816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple primary tumors (MPTs) are rare in dogs and challenging to diagnose when distinct lesions coexist. A 9-year-old mixed-breed female presented with mammary and cutaneous masses. Imaging revealed no pulmonary metastasis but metallic foreign bodies. Histopathology identified a low-grade intraductal carcinoma (HER2-negative), melanosis with borderline proliferative features in an inguinal lymph node, and benign acrochordons. Immunohistochemistry confirmed S100 positivity and elevated Ki-67 in the melanocytic component, suggesting melanocytic lesion with borderline proliferative features. Treatment included bilateral mastectomy, lymph node excision, and chemotherapy. Post-treatment bloodwork showed mild cytopenias and biochemical changes consistent with hepatocellular stress. No recurrence or metastasis occurred within 6 months. This case highlights the role of multimodal diagnostics in distinguishing MPTs from metastasis and guiding therapy in complex geriatric oncology cases.

Indexed as

breast cancerchemotherapyimmunohistochemistrymultiple primary tumors (MPTs)veterinary oncology

Identifiers

PMID42553616
PMCPMC13435256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.