ArticleOpen forum infectious diseases2026
Clinical Features of Clostridial Necrotizing Soft-tissue Infections: Analysis of a Prospective Scandinavian Cohort Study.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Necrotizing soft-tissue infections (NSTI) caused by Method: We identified all clostridial cases from the INFECT cohort, a prospective study including patients with confirmed NSTI admitted to 5 Scandinavian referral hospitals over a 4-year period. Selected parameters were compared to a control group of nonclostridial polymicrobial infections. Additionally, we analyzed polymicrobial infections with clostridial species. Results: Ten cases of clostridial NSTIs were identified, evenly divided between cases caused by Conclusions: Clostridial NSTIs were associated with extremity infection, immunodeficiency, and penetrating trauma. The cases demonstrate a wide spectrum of severity. In polymicrobial NSTIs involving
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