ArticleNAR genomics and bioinformatics2026
The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance.
Article in NAR genomics and bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Inaccurate allele and gene expression counts due to map bias and genome ambiguity lead to high false positive and false negative rates in studies of allelic imbalance. We demonstrate that long read RNA sequencing (RNA-seq) and straightforward quality control measures can be used to reduce bias in allele counts in case studies from four species:
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