Evidence map›Paper›PMID 42553512›Full record

ArticleWomen's health reports (New Rochelle, N.Y.)

Longitudinal Changes in Fear Learning across Pregnancy: Moderation by Sexual Trauma.

Mariana Rocha, Sriya Karra, Meghna Ravi, Sean T Minton, Natalie Merrill, Rebecca Hinrichs, Nicole R Nugent, Emma C Lathan, Shimarith Wallace, Suchitra Chandrasekaran and 3 more

Abstract read
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mariana RochaDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-4141-7489
Sriya KarraDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-2625-7667
Meghna RaviDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Sean T MintonDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Natalie MerrillDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Rebecca HinrichsDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Nicole R NugentBrown University, Providence, Rhode Island, USA.
Emma C LathanDepartment of Psychological Sciences, Auburn University, Auburn, Alabama, USA.
Shimarith WallaceDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Suchitra ChandrasekaranDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Alicia K SmithDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Vasiliki MichopoulosDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
The effects of pregnancy on post traumatic symptoms and fear physiology in traumatized African American womenR01MH115174 · NIMH · EMORY UNIVERSITY · PI MICHOPOULOS, VASILIKI · 2018 to 2022
$3.7M
NIH HHS P51 OD011132NIMH NIH HHS R01 MH115174
6 · The paper itself

Abstract

Background: Black pregnant individuals are at increased risk for posttraumatic stress disorder (PTSD), symptoms that may be exacerbated by histories of sexual trauma. Disruptions in fear learning are central to the development and maintenance of PTSD. The present study examined longitudinal changes in fear acquisition and extinction over pregnancy, and the moderating role of sexual trauma in fear learning trajectories, in a sample of under-resourced Black pregnant persons. Methods: Participants ( Results: Linear mixed models showed that percent potentiation to the danger cue during acquisition increased over pregnancy in the general sample ( Conclusions: These findings suggest that pregnancy progression is adaptive by enhancing startle responses to danger cues during fear acquisition, and that high levels of sexual trauma exposure may attenuate typical changes in threat sensitivity that occur during pregnancy.

Indexed as

electromyographyextinctionfear learningpregnancysexual trauma

Identifiers

PMID42553512
PMCPMC13434897

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.