Evidence map›Paper›PMID 42553460›Full record

ArticleVeterinary medicine international2026

Unraveling the Molecular Landscape of Follicular Fluid: A Comparative Proteomic Study Between Bali and Brahman Cattle.

Sri Gustina, Hasbi Hasbi, Ismah Ulfiyah Azis, Tulus Maulana, Siti Nuraisya Hamsir

Abstract read
In one paragraph

Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sri GustinaDepartment of Animal Production, Faculty of Animal Science, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10 Tamalanrea, Makassar 90245, South Sulawesi, Indonesia, unhas.ac.id.ORCID https://orcid.org/0000-0003-1466-4740
Hasbi HasbiDepartment of Animal Production, Faculty of Animal Science, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10 Tamalanrea, Makassar 90245, South Sulawesi, Indonesia, unhas.ac.id.ORCID https://orcid.org/0000-0002-6069-2171
Ismah Ulfiyah AzisDepartment of Animal Nutrition, Faculty of Animal Science, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10 Tamalanrea, Makassar 90245, South Sulawesi, Indonesia, unhas.ac.id.ORCID https://orcid.org/0009-0002-3675-3234
Tulus MaulanaResearch Center for Applied Zoology, National Research and Innovation Agency, Jl. Raya Bogor Km. 46, Cibinong 16911, Indonesia, brin.go.id.ORCID https://orcid.org/0000-0002-5578-3992
Siti Nuraisya HamsirMagister Programme in Animal Science and Technology, Faculty of Animal Science, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10 Tamalanrea, Makassar 90245, South Sulawesi, Indonesia, unhas.ac.id.ORCID https://orcid.org/0009-0003-4584-7117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Protein biomarkers are increasingly recognized as indicators of metabolic status, immune response, and reproductive performance in cattle. However, comparative data among different breeds commonly raised in Indonesia remain limited. Objectives: This study aimed to compare the specific proteins in follicular fluid (FF) of Bali and Brahman cows. Methods: Samples from FF ( Results: Proteomic analysis revealed distinct breed-specific FF profiles, with 16 proteins uniquely identified in Bali cattle and 23 proteins in Brahman. Bali FF was enriched with proteins associated with protease inhibition, coagulation regulation, extracellular matrix remodeling, and cytoskeletal dynamics, including CORO1C, ZER1, YARS1, and L3MBTL3. In contrast, Brahman FF showed enrichment of proteins involved in lipid oxidation, one-carbon metabolism, and peroxisomal activity, notably ACOX2, BHMT, and KIAA0586. Conclusion: Here, we present the proteomic characterization of FF from Bali and Brahman cattle, where several bioactive proteins are candidate proteins potentially associated with reproductive processes. These findings highlight the potential of protein biomarkers in guiding cattle breeding and management strategies in tropical regions.

Indexed as

Bali cattlebiomarker proteinsBrahman cowsfollicular fluidproteomic

Identifiers

PMID42553460
PMCPMC13435373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.