ArticleCureus2026
A Rare Cause of Breast Pain in Primary Care: Mondor's Disease Diagnosed in a Family Medicine Clinic.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Mondor's disease is a rare disease that presents as a superficial thrombophlebitis that most often occurs in breast tissue, but can also occur on the anterior chest wall, thoracoabdominal region, and even the penis. Mondor's disease generally presents as localized pain and a palpable cord-like structure. It is a benign and self-limiting disease that can be managed conservatively and typically resolves in about four weeks without any treatment. This condition is important to recognize clinically because it can easily be mistaken for lymphangitis, cellulitis, musculoskeletal chest wall pain, breast mass, or malignancy. We present the case of a 58-year-old female who presented to the family medicine clinic with a several-day history of bilateral breast pain. The patient had a prompt mammogram that was negative and breast ultrasound imaging that revealed a small thrombus in the left breast, suggesting Mondor's disease as the culprit. The patient was treated conservatively and provided with close breast ultrasound follow-up. The patient's symptoms improved and resolved over 12 weeks. This case highlights the importance for primary care physicians to remain attentive to red flags requiring further investigation and recognize Mondor's disease in primary care.
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