Evidence map›Paper›PMID 42553319›Full record

ArticleFrontiers in neurology

Degeneration rather than hypoplasia may be the pathologic feature of the endolymphatic sac in patients with ipsilateral delayed endolymphatic hydrops.

Kaijun Xia, Ping Lei, Qin Liu, Yingzhao Liu, Cen Chen, Xiaoye Chen, Xingqian Shen, Ziying Xu, Bo Liu, Hongjun Xiao and 1 more

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In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Kaijun Xia *Department of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ping Lei *Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qin LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yingzhao LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cen ChenDepartment of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaoye ChenDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xingqian ShenDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ziying XuDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bo LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hongjun XiaoDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yangming LengDepartment of Otorhinolaryngology-Head and Neck Surgery, ENT Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Delayed endolymphatic hydrops (DEH) and Ménière's disease (MD) are both hydropic ear disease. In MD patients, the endotypes of MD are classified based on pathological types of the endolymphatic sac (ES), which can be distinguished by a radiological indicator: the angular trajectory of the vestibular aqueduct (ATVA). Studies have exhibited that MD patients of different pathological types of ES manifest different clinical characteristics. Here, we aimed to investigate the prevalence of each ATVA category in DEH and MD, and to further explore the clinical significance of ATVA in ipsilateral DEH patients. Methods: Twenty-seven ipsilateral DEH patients, 114 unilateral MD patients and 45 control participants were enrolled in the present study. The ATVA was determined using temporal bone CT imaging. Clinical features, including gender, age and the caloric test results, were collected. The prevalence of ATVA categories were compared between patients with ipsilateral DEH and unilateral MD. The association between ATVA and clinical features was also examined. Results: (1) Compared to MD-affected ears, ATVA ≤ 120° was more frequent (χ Conclusion: Compared to unilateral MD patients, degenerative ES may be the dominant pathological type in ipsilateral DEH patients due to the high occurrence of ATVA ≤ 120°.

Indexed as

angular trajectory of the vestibular aqueductdelayed endolymphatic hydropsendolymphatic Hydropsendolymphatic sacMénière’s disease

Identifiers

PMID42553319
PMCPMC13433524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.