Evidence map›Paper›PMID 42553301›Full record

ArticleCircular economy and sustainability2026

Mapping Uncertain Risks and Impacts of Substances of Concern in Product Life Cycles - An SSbD Tool for Product Developers.

Julieta Bolaños Arriola, Maaike Weber, Nina van Dulmen, Jeroen Guinée, Martina G Vijver, Ruud Balkenende

Abstract read
In one paragraph

Article in Circular economy and sustainability, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julieta Bolaños ArriolaFaculty of Industrial Design Engineering, Department of Sustainable Design Engineering, Delft University of Technology, Landbergstraat 15, Delft, CE 2628 The Netherlands.ORCID 0009-0004-5198-6743
Maaike WeberFaculty of Industrial Design Engineering, Department of Sustainable Design Engineering, Delft University of Technology, Landbergstraat 15, Delft, CE 2628 The Netherlands.ORCID 0009-0005-9461-9422
Nina van DulmenInstitute of Environmental Sciences (CML), Leiden University, Einsteinweg 2, Leiden, CC 2333 The Netherlands.ORCID 0009-0009-2059-3564
Jeroen GuinéeInstitute of Environmental Sciences (CML), Leiden University, Einsteinweg 2, Leiden, CC 2333 The Netherlands.ORCID 0000-0003-2558-6493
Martina G VijverInstitute of Environmental Sciences (CML), Leiden University, Einsteinweg 2, Leiden, CC 2333 The Netherlands.ORCID 0000-0003-2999-1605
Ruud BalkenendeFaculty of Industrial Design Engineering, Department of Sustainable Design Engineering, Delft University of Technology, Landbergstraat 15, Delft, CE 2628 The Netherlands.ORCID 0000-0002-5990-3955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current Safe and Sustainable by Design (SSbD) frameworks, such as those proposed by the Joint Research Centre, support the development of safer, more sustainable substances, materials, and manufacturing processes. However, these were not designed for product developers or designers and therefore do not align with the iterative and creative nature of product development, nor with its specific needs and constraints. Broad adoption of SSbD requires tiered, resource-efficient assessments tailored to the specific needs of different professionals. The product developer's perspective is essential for creating safer, more sustainable products, enabling context-specific evaluation of chemical applications, substances of concern (SoC), and product life cycles. In a circular economy, where products, parts, and materials circulate, holistic views become critical, as emissions and exposures may increase and accumulate. Therefore, we developed the Mapping Assessment for Product Substance Safety and Sustainability (MAPSSS) tool, which integrates principles of Life Cycle Assessment (LCA) and Risk Assessment (RA) into a product development context. Through iterative development based on real-life cases of products containing SoC, we combined essential elements of RA and LCA into a product development workflow. Expert input on environmental assessment and ecotoxicology informed each iteration of the process. MAPSSS supports product developers in identifying and assessing SoC risks, trade-offs, uncertainty levels, and environmental impacts across the product life cycle. It enables the identification of risk hotspots in reference products, supporting mitigation strategies and comparison with new solutions. This represents an initial step toward a product-specific SSbD assessment tool for early design stages. Supplementary Information: The online version contains supplementary material available at 10.1007/s43615-026-01077-w.

Indexed as

Design methodHazardous chemicalsProduct designRisk assessmentSafe and sustainable by designSubstances of concern

Identifiers

PMID42553301
PMCPMC13433538

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.