Evidence map›Paper›PMID 42553295›Full record

ArticleFrontiers in public health2026

Life-course restructuring of infectious mortality in China, 2004-2021: a national surveillance study.

Liu Binglian, Chen Aowen, Yang Yuting, Huang Changquan, Zhang Xingping

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Liu BinglianSichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Chen AowenSichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Yang YutingSichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Huang ChangquanSichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Zhang XingpingSichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While China has achieved significant milestones in controlling infectious diseases, how mortality patterns have shifted across different life stages remains poorly understood. This study aims to delineate the evolving burden of infectious disease mortality to inform age-specific public health strategies. Methods: We analyzed national death surveillance data from China spanning 2004 to 2021. "Combined infectious mortality" was defined as the aggregate of communicable and parasitic diseases plus respiratory infections. Focusing on four key categories-respiratory infections, tuberculosis, viral hepatitis, and HIV/AIDS-we calculated crude and age-standardized mortality rates (ASMR). Log-linear regression models estimated annual percentage changes (EAPCs). Primary trend inferences were restricted to 2013-2019 (stable post-expansion period); 2020-2021 was treated separately due to the absence of a COVID-19 code. Results: During 2013-2019, mortality declined substantially faster in younger than in older age groups: EAPC was -14.70% (95% CI -16.96 to -12.38) for children aged 0-4 years, but only -1.62% (95% CI -3.66 to 0.46) for adults aged 75 + (interaction Conclusion: China is undergoing a distinctive epidemiological transition: infectious deaths are increasingly concentrated in older age groups, driven primarily by divergent age-specific mortality trends rather than population ageing alone. Public health strategies must extend beyond maternal-child health frameworks to address growing vulnerabilities in older populations-particularly respiratory infections and HIV in ageing rural communities.

Indexed as

Communicable DiseasesMortalityAdolescentAdultAgedChildChild, PreschoolChinaFemaleHumansInfantInfant, NewbornMaleMiddle AgedPopulation SurveillanceYoung AdultChinaHIV/AIDSinfectious mortalitylife courserespiratory infectionstuberculosisviral hepatitis

Identifiers

PMID42553295
PMCPMC13433531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.