ArticleFrontiers in cardiovascular medicine2026
Giant chronic splenic infarction mimicking splenic neoplasm in a patient with rheumatic heart disease: a case report.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Giant chronic splenic infarction is an extremely rare condition with insidious onset and atypical imaging features, carrying a high risk of misdiagnosis as splenic neoplasm. This case highlights the atypical clinical features and important diagnostic considerations of this uncommon disorder. Case description: A 73-year-old female presented with recurrent epigastric pain for 2 years, with a medical history of rheumatic heart disease and hypertension. Contrast-enhanced abdominal computed tomography showed a huge splenic mass measuring approximately 18.0 × 14.2 × 19.1 cm with heterogeneous enhancement and calcification, which was highly suggestive of splenic neoplasm. The patient received splenectomy, and pathological examination confirmed extensive splenic infarction with focal fibrosis and calcification. The patient had an uneventful postoperative recovery, with no evidence of thrombosis or infectious complications during the 3-month follow-up period. Conclusion: Rheumatic heart disease with mitral stenosis may have contributed to splenic infarction as a possible cardioembolic source in this patient. Giant chronic splenic infarction may be misdiagnosed because of atypical clinical manifestations, tumor-mimicking imaging features, and insufficient integration of clinical, laboratory, and imaging findings. A comprehensive assessment of clinical history, laboratory results, imaging findings, and cardiac status may help reduce misdiagnosis and guide appropriate management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.