ArticleFrontiers in veterinary science2026
Phenotypic antimicrobial susceptibility and genomic resistance determinants in canine otitis-associated
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Phenotypic Susceptibility, Resistance-Associated Genomic Determinants, and Mobile-Genetic-Element Context of Canine Otitis Externa-AssociatedVeterinary sciences · 2026Article
- A conserved virulence backbone and heterogeneous type III secretion effector profiles in historical canine otitis-associatedFrontiers in veterinary science · 2026Article
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Authors and funding
8 authors.
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Abstract
Background: Methods: This study integrated broth microdilution-based minimum inhibitory concentration (MIC) testing with whole-genome analysis to characterize antimicrobial susceptibility patterns and genomic resistance determinants in canine otitis-associated Results: High frequencies of elevated MICs were detected for several clinically relevant agents. The highest proportions above interpretive thresholds were observed for enrofloxacin (109/110, 99.1%), marbofloxacin (99/110, 90.0%), piperacillin-tazobactam (75/110, 68.2%), ceftazidime (71/110, 64.5%) and tobramycin (62/110, 56.4%). The median modified multiple-antimicrobial-resistance index, calculated only from agents with interpretable resistance thresholds, was 0.56. Genomic analysis showed a broad intrinsic resistance background dominated by efflux-associated determinants and recurrent aminoglycoside, beta-lactam and fluoroquinolone-associated genes, including Conclusion: These findings support the need for culture- and MIC-guided therapy in canine
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