Evidence map›Paper›PMID 42552802›Full record

ArticleElectrophoresis2026

High-Throughput Multi-Capillary Electrophoresis.

Jana Drewes, Sarah Meyer, Isobel Roberts, Cleo Fanny, Philip A Doble, Dayanne Mozaner Bordin, Janice I McCauley

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Electrophoresis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jana DrewesInstitute of Inorganic and Analytical Chemistry, University of Münster, Münster, Germany.
Sarah MeyerSCIEX Oceania, Melbourne, Victoria, Australia.
Isobel RobertsSchool of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.
Cleo FannyToulouse INP-ENSIACET, Toulouse, France.
Philip A DobleSchool of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.
Dayanne Mozaner BordinSchool of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.
Janice I McCauleySchool of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.

Funding

Mikos family
6 · The paper itself

Abstract

The potential of multi-capillary electrophoresis (CE) for high-throughput analysis of legacy CE applications was investigated by optimisation of the separation of six pharmaceutical compounds on a single-capillary instrument, followed by transference of the method to an eight-capillary BioPhase 8800 system from SCIEX. Multi-CE had superior performance, allowing construction of calibration curves in a single run, and a five-fold reduction of run time per sample, improved linearity, accuracy and limits of detection. Method transfer from the single-capillary system required minor instrumental parameter adjustments using the same background electrolyte. The potential of multi-CE was shown via quantification of caffeine in a variety of energy drinks, demonstrating broad applicability where high-throughput and rapid analyses are desirable.

Indexed as

High-Throughput Screening AssaysCaffeineElectrophoresis, CapillaryLimit of DetectionLinear ModelsReproducibility of ResultsCaffeineanalytical chemistrycalibration curvecapillary actioncapillary electrophoresischemistrychromatographydetection limitelectrolyteelectrophoresislinearity

Identifiers

PMID42552802
PMCPMC13572887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.