ArticleDigestive diseases and sciences2026
Outcomes of ERCP for Post-operative Bile Leaks After Cholecystectomy, Hepatectomy, and Liver Transplantation: A High-Volume Tertiary Referral Center Experience.
Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- ERCP for Post-operative Bile Leaks: One Answer to Three Different Questions.Digestive diseases and sciences · 2026Article
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Authors and funding
16 authors.
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Abstract
backgroundBile leak (BL) remains one of the major adverse events of hepatobiliary surgeries. We evaluated ERCP outcomes for postoperative BL (PBL) cholecystectomy (C-BL), hepatectomy (H-BL), and liver transplantation (LT-BL) and identified predictors of persistent leak after initial ERCP.
methodsThis study includes consecutive patients who underwent ERCP for PBL at a single high-volume center (2011-2021). Leaks were graded as low-grade BL (LG-BL) or high-grade BL (HG-BL). Initial success was defined as cholangiographic and clinical resolution of BL following a single therapeutic ERCP session at the first follow-up ERCP. Final success was defined as cholangiographic and clinical resolution of the BL at the last follow-up assessment, irrespective of the number of therapeutic ERCP sessions required.
results417 patients with PBLs were included: 348 (83.5%) C-BL, 43 (10.3%) H-BL, and 26 (6.2%) LT-BL. Initial clinical success was 80.7% overall, with the highest in LT-BL (91.7%), followed by C-BL (83.5%), and then H-BL (50%) (p < 0.001). HG-BLs had lower initial success (54.7% vs. 87.8% for LG-BL; p < 0.001). Final success was 96% overall, but lower in H-BL (84.2%) than C-BL (97.3%) and LT-BL (95.8%) (p < 0.001). Overall, HG-BL (adjusted odds ratio [aOR] 5.79) and H-BL (aOR 3.52) were independent predictors of persistent leak.
conclusionERCP is effective and safe for PBL. However, initial clinical success varied by surgical etiology and leak severity. HG-BL and H-BL were associated with lower initial success and more frequently required repeated ERCP interventions for leak resolution. Further studies are needed to validate optimal treatment strategies for higher-risk bile leak subgroups.
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