Evidence map›Paper›PMID 42552232›Full record

Trial reportEarly intervention in psychiatry2026

Feasibility Trial of a Health Behaviours Promotion Group for Youth at Clinical High Risk for Psychosis.

Bernalyn Ruiz-Yu, Tanya Diaz, Daniella Hernandez, Jamie Zinberg, David J Miklowitz, Carrie E Bearden

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Early intervention in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05532683 (Development and Feasibility of a Lifestyle Group Intervention for Youth at Clinical High Risk for Psychosis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05532683 nacompletednot on this map

Development and Feasibility of a Lifestyle Group Intervention for Youth at Clinical High Risk for Psychosis

TypeinterventionalSponsorUniversity of California, Los AngelesRan2023 to 2024Enrolled9ConditionsProdromal Schizophrenia, Psychosis, Psychological Disorder, Psychological StressArmsHealth Behaviors Group
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bernalyn Ruiz-YuDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tanya DiazDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.
Daniella HernandezDepartment of Psychology, University of California, Los Angeles, California, USA.
Jamie ZinbergDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.
David J MiklowitzDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-9647-6147
Carrie E BeardenDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-8516-923X

Funding

ProNET: Psychosis-Risk Outcomes NetworkU01MH124639 · NIMH · YALE UNIVERSITY · PI CARRIE E BEARDEN, JOHN M KANE · 2020 to 2026
$81.2M
Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy TrialR01MH123575 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, MIKLOWITZ, DAVID JAY · 2020 to 2023
$5.4M
Neurodevelopment and Psychosis in the 22q11.2 Copy Number VariantsR37MH085953 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARRIE E BEARDEN · 2023 to 2026
$2.9M
Clinical Research Training in Schizophrenia and Other PsychosesT32MH122395 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KEITH H NUECHTERLEIN · 2021 to 2026
$1.8M
Levin Trust and Shear Family FoundationNIMH NIH HHS R01MH123575NIMH NIH HHS R37MH085953NIMH NIH HHS T32 MH122395NIMH NIH HHS U01MH124639Stephen R. Mallory Schizophrenia Research Award
6 · The paper itself

Abstract

backgroundDevelopment of new evidence-based interventions for youth who are at clinical high risk for psychosis (CHR-P) is needed. Health behaviours and lifestyle habits such as physical activity, sleep, and substance abuse are modifiable risk factors for a variety of health outcomes. We assessed the feasibility and acceptability of a novel health behaviour-focused psychosocial intervention for youth at CHR-P.

methodsIn a non-randomized feasibility trial, youth aged 13-17 who met CHR-P criteria participated in a 9-week health behaviour promotion group that provided psychoeducation and skills training regarding stress management, sleep, physical activity, nutrition, mitigating substance use, and health behaviour goal setting. Primary outcomes included feasibility and pre-to post-intervention change in health behaviours and symptoms. The secondary outcome explored the social validity of the intervention.

resultsOut of 18 invited participants, seven enrolled, and five completed at least two-thirds of the intervention, indicating modest feasibility and good retention in those who enrolled. There were no significant pre-post changes across measures of health behaviours or symptoms. Participants endorsed the goals of the intervention as meaningful and congruent with their treatment goals. Among those who enrolled, the group format was described as acceptable, while the didactic style was less preferred. DISCUSSION: Findings of this study showed the intervention to be modestly acceptable and feasible. Changes in health behaviours and symptoms were not significant but trended in the expected direction. Future trials are needed to refine the intervention and assess effectiveness.

trial registrationClinicaltrials.gov Identifier: NCT05532683.

Indexed as

Health BehaviorHealth PromotionPsychotic DisordersAdolescentFeasibility StudiesFemaleHumansMale

Identifiers

PMID42552232
PMCPMC13437250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.