Evidence map›Paper›PMID 42552091›Full record

ArticleLife science alliance2026

Bruno 1 remodels P-bodies to protect select mRNAs during the early ER stress response.

Samantha N Milano, Livia V Bayer, Julie J Ko, Gwendolyn S Posner, Albina H Granovsky, Diana P Bratu

Abstract read
In one paragraph

Article in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samantha N MilanoDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA.
Livia V BayerDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA.
Julie J KoDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA.
Gwendolyn S PosnerDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA.
Albina H GranovskyDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA.
Diana P BratuDepartment of Biological Sciences, Hunter College, City University of New York, NY, USA bratu@genectr.hunter.cuny.edu.ORCID https://orcid.org/0000-0002-8273-5961

Funding

Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Characterizing P-bodies assembly and coordination of mRNA fate during Drosophila melanogaster oogenesisSC1GM135132 · NIGMS · HUNTER COLLEGE · PI BRATU, DIANA P. · 2020 to 2023
$1.6M
NIGMS NIH HHS R01 GM084947NIGMS NIH HHS SC1 GM135132
6 · The paper itself

Abstract

P-bodies are cytoplasmic membraneless organelles involved in mRNA storage, yet their role in cellular stress responses remains unresolved. Here, we demonstrate that P-bodies are remodeled during the early response to ER stress throughout

Indexed as

Drosophila ProteinsEndoplasmic Reticulum StressRNA-Binding ProteinsRNA, MessengerAnimalsDrosophila melanogasterOogenesisSignal TransductionUnfolded Protein ResponseDrosophila ProteinsRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID42552091
PMCPMC13438841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.