Evidence map›Paper›PMID 42551142›Full record

ReviewInternational journal of paleopathology2026

Beyond the surface: A review of current and potential micro-CT applications in paleopathology.

Jennifer H Lowell, Katherine D Van Schaik

Erratum issuedAbstract readReview
In one paragraph

Review in International journal of paleopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jennifer H LowellQuillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
Katherine D Van SchaikDepartment of Radiology & Radiological Sciences, Department of Classical and Mediterranean Studies, Vanderbilt University, Nashville, TN, USA. Electronic address: katherine.d.van.schaik@vumc.org.

Funding

Mechanistic association of epigenetic bone age and frailty measures with bone imaging studies using novel artificial intelligence approaches - Research Continuity and Retention SupplementK08AG088493 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Katherine Douglas Van Schaik · 2025 to 2026
$375k
NIA NIH HHS K08 AG088493
6 · The paper itself

Abstract

objectiveWe assess the current use and future potential of micro-computed tomography (micro-CT) in bioarchaeology and paleopathology, identifying areas of underuse and offering recommendations for effective, standardized application. MATERIALS: We reviewed articles published 2015-2025 in the International Journal of Paleopathology and International Journal of Osteoarchaeology, supplemented by the Journal of Archaeological Science and Journal of Archaeological Science: Reports (2015-2025) and five frequently cited mummy studies (2010-2025).

methodsArticles were categorized by how micro-CT was used (active use versus referencing or recommending it) and by anatomical and pathological focus; reporting of acquisition and reconstruction parameters was also evaluated.

resultsAcross all journals, micro-CT was used predominantly to image bone, with little application to soft tissue, infectious disease, or malignancy, and parameter reporting was inconsistent across studies.

conclusionsMicro-CT is underused for soft-tissue, infectious, and neoplastic pathologies; its diagnostic value would expand with standardized parameter reporting and closer collaboration with radiologists. SIGNIFICANCE: This review maps current micro-CT use in paleopathology and offers practical guidance, a reporting checklist, and parameter recommendations to support broader, more reproducible adoption of this potentially diagnostic imaging modality. LIMITATIONS: The review focused on a defined set of journals and a non-exhaustive selection of mummy studies. SUGGESTIONS FOR FURTHER RESEARCH: Future work should develop consensus reporting protocols by tissue type and explore AI-assisted analysis of micro-CT data.

Indexed as

PaleopathologyX-Ray MicrotomographyHumansMummiesImaging parametersInfectious diseaseMetabolic diseasesMummified remainsNeoplasm

Identifiers

PMID42551142
PMCPMC13473989

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.