Sphingosine synergizes with polymyxin antibiotics against

Jacob R Mackinder, Meghan Quinlan, Matthew J Wargo

Abstract read

In one paragraph

Article in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jacob R MackinderDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.

Meghan QuinlanDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.

Matthew J WargoDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is an increasing threat to global health. However, there is a limited set of antibiotics that are effective against drug-resistant Gram-negative bacteria like

Indexed as

Anti-Bacterial AgentsKlebsiella pneumoniaePolymyxinsPseudomonas aeruginosaSphingosineColistinDrug SynergismHumansMicrobial Sensitivity TestsPolymyxin BAnti-Bacterial AgentsColistinPolymyxin BPolymyxinsSphingosineantibiotic synergyantimicrobial resistancepolymyxinsphingosine

Identifiers

PMID42550589

DOI10.1099/mic.0.001743

PMCPMC13440347

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.