ArticleJournal of magnetic resonance imaging : JMRI2026
Cardiac MR Characterization of Infarct-Related and Remote Myocardial Injury in Multivessel Disease After Acute Myocardial Infarction.
Article in Journal of magnetic resonance imaging : JMRI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial for "Cardiac MR Characterization of Infarct-Related and Remote Myocardial Injury in Multivessel Disease After Acute Myocardial Infarction".Journal of magnetic resonance imaging : JMRI · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
backgroundPatients with multivessel disease (MVD) after acute myocardial infarction (AMI) have worse outcomes than those with single-vessel disease (SVD), but whether MVD is associated with diffuse myocardial injury beyond the infarct zone (IZ) remains unclear. PURPOSE: To characterize infarct-related and remote myocardial tissue properties using cardiac MRI in patients with MVD compared with SVD after AMI, and to explore differences according to revascularization completeness. STUDY TYPE: Retrospective. POPULATION: Two hundred and twenty-four patients with AMI who underwent MRI within 31-90 days after percutaneous coronary intervention (90 SVD, 42 MVD with complete revascularization [CR], and 92 MVD with incomplete revascularization [IR]). FIELD STRENGTH/SEQUENCES: 3.0 T; balanced steady-state free precession cine, phase-sensitive inversion recovery late gadolinium enhancement (LGE), modified Look-Locker (pre- and post-contrast T1-mapping), and gradient and spin echo (T2-mapping) sequences. ASSESSMENT: Left ventricular volumes and function (cine), infarct size (LGE), and myocardial tissue parameters (native T1 and extracellular volume [ECV], and T2) were quantified in IZ, peri-infarct zone (PIZ), and remote zone (RZ) using standardized methods. STATISTICAL TESTS: Group comparisons used Student's t-test or Mann-Whitney U test for continuous variables and χ
resultsCompared with SVD, MVD showed larger infarct size (p < 0.001), and higher native T1, ECV, and T2 values in PIZ (p = 0.034, 0.004, 0.005) and RZ (p = 0.041, < 0.001, < 0.001). After adjustment for clinical covariates (age, diabetes, hyperlipidemia, BMI) and infarct size, these differences in RZ remained significant. Among patients with MVD, infarct size and ventricular function did not differ between CR and IR groups (p = 0.661, 0.494, 0.857). However, MVD-IR was associated with significantly higher ECV-PIZ (p = 0.023), ECV-RZ (p = 0.025) and T2-RZ (p = 0.003). DATA
conclusionsIn AMI, MVD was associated with diffuse myocardial injury extending beyond the IZ. Differences related to revascularization completeness predominantly involved non-infarct myocardium. LEVEL OF EVIDENCE: 3: TECHNICAL EFFICACY: Stage 2.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.